Synbiotic 365

1,214 reviews

Synbiotic 365 is the 3-in-1 gut health solution made with 14 probiotics, herbal prebiotics, and B vitamins.

  • Get 11% off and free shipping forever
  • Modify, skip, or cancel anytime
  • 30-day money back guarantee



Synbiotic 365 is the daily all-in-one prebiotic and probiotic gut health solution made from the finest natural ingredients in the world. This proprietary formula includes 14 powerful probiotic strains, an herbal prebiotic, and a concentrated blend of B vitamins — to help balance your gut microbiome, support healthy digestion, support healthy energy metabolism, and support your weight goals.

  • 30 delayed-release gel capsules
  • No refrigeration required
  • 20 billion CFU (at time of manufacturing)
  • Non-GMO
  • Vegan Certified
  • Allergen Free
  • Formulated in the USA with Internationally-Sourced Ingredients
Supplement Facts

How to Use

  1. 1Take 1 capsule with 8 oz. of water on an empty stomach, 30 minutes before eating.

ingredient spotlight

Lactobacillus gasseri BNR17

This potent probiotic strain has over 20 years of clinical research behind it. Studies have shown that it supports gut health and can even help to reduce waist and hip circumferences.

Explore Ingredient Spotlight
Lactobacillus gasseri BNR17

Benefits of taking Synbiotic 365®

14 probiotic strains with 20 billion CFU

We added 14 unique strains of therapeutic-class probiotics, each selected for their clinically-backed effects on colonizing the gut with good bacteria, improving the functioning of the digestive tract, supporting and protecting the gut lining, and increasing gut biodiversity.

Aids in immune system performance

DE111 at 1 billion CFU to support and boost healthy immune system function. The presence of good bacteria encouraged by Synbiotic 365 further enhances and promotes your immune system’s performance.

Promotes a healthy digestive system

A combination of clinically proven probiotic strains and herbal prebiotics work together to discourage the growth of bad bacteria and boost the vitality and growth of good bacteria for improved functioning of the digestive tract and support of digestive comfort.

Supports weight management goals

Having the proper balance of good bacteria in your gut helps your system break down and digest foods quicker and easier. Better digestive function helps with metabolic health to support weight management.

Boosts metabolism

Synbiotic 365 contains essential B-complex vitamins, which helps prevent mental fatigue and support the metabolism of carbohydrates, amino acids, and fats.

nourishes gut lining and improves energy

Synbiotic 365 is perfect if...

  • You’ve tried other probiotics and prebiotics but still haven’t found a product that works for you.
  • You are looking for an all-in-one product that provides daily maintenance to cover the daily basics of gut health.
  • You want better digestion, less gas, bloating, and regularity.
  • You’re trying to lose weight but dieting and exercise aren’t helping.
  • You’re experiencing Leaky Gut, feeling sluggish and foggy-brained, and want more energy during the day.
  • You want to boost your gut flora and improve your digestive function.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

related products

Frequently purchased with



Nutrient Absorption

Starts at

Select Your Package:

Add to Cart
GutConnect 365

GutConnect 365

Gut Integrity.

Starts at

Add to Cart


Gut Balance Kit

Starts at

Select Your Package:

Add to Cart


Based on 1,214 Reviews

  • 5
  • 4
  • 3
  • 2
  • 1

Darla P.

on Feb 19, 2024

My son has been using the Synbiotic 365 for awhile now with great results. He has not had gut issues and not sensitive to Gluten and dairy anymore. I got this for my daughter recently and has had good results so far. I think it takes a month or so before exact results. Very happy with it!

Kristine L.

on Feb 17, 2024

So far so good, I have been using probiotics for years but 365 seems to really work the best.

Kelsea H.

on Feb 17, 2024

I have IBS and this is the only supplement I’ve found that helps

Margaret R.

on Feb 13, 2024

I seem to have more energy.

Karen P.

on Feb 13, 2024

Excellent product

Marcia P.

on Feb 12, 2024

I have been taking the Symbiotic 365 for about 3 weeks and have noticed a big difference in my gut function. I was looking for a probiotic containing a combination of important bacterial strains that includes L. reuteri and have not been disappointed. Your product was recommended by Dr. William Davis who I follow for diet and gut health. I also like the periodic articles from Dr. Stork which help me stay focused on my regimen.

Andrea R.

on Feb 08, 2024

Symbiotic 365 is a quality product and contributes greatly to a healthy good flora balance and elimination. I love that Chicory and all the B's are included in this product.

Candyce A.

on Feb 04, 2024

I have been taking Symbiotic 365 for over 4 years now, and I have absolutely no gut issues. It’s a good product.

Kevin M.

on Feb 03, 2024

Order was delivered sooner than expected.

Deborah W.

on Feb 02, 2024

Very pleased with the product. Keeps system regular. Would recommend for gut health.