








OralBiome365 is perfect if…
- You want a natural and refreshing way to strengthen your teeth, gums, and oral health.
- You’re struggling with occasional digestive concerns and want to restore balance to your gut microbiome.
- You want to freshen your breath naturally while supporting the good bacteria in your mouth.
- You’re looking for an easy, all-in-one solution to boost your immune system daily.
- You’re tired of juggling multiple supplements and want a convenient 3-in-1 chewable for oral, gut, and immune health.
30-Day Money Back Guarantee
We stand behind all of our Nature M.D. products. We offer a 100% money-back guarantee if you are not completely satisfied. Just return the unused portion to us within 30 days for a full refund. It’s as simple as that! Visit our FAQ page for additional information.

Adults Chew 1-2 capsules per day
It supports both oral and gut health by balancing the mouths microbiome, improving digestion and promoting a stronger immune system. It helps to prevent issues like gum inflammation, bad breath, and leaky gut while boosting nutrient absorption.
1-2 weeks you will notice fresher breath and improved gum health. For noticable improvements in digestive heatlh, it can take 3-4 weeks of consistent use.
It is great for anyone looking to improve overall oral hygiene, digestive health and immune function.
It is Certified Vegan, soy free, Non-GMO, dairy free, sugar free, and gluten free.
We recommend you consult with your physician. All of our products are made with natural ingredients.
It’s always best to consult a doctor before taking any supplement, including Oral Biome, during pregnancy or while nursing. Although probiotics are generally considered safe, every pregnancy is different, and a healthcare professional can provide personalized advice to ensure both the mother's and baby’s health are prioritized. Always check with a doctor before introducing new products while pregnant or breastfeeding.
Recurring deliveries keep you consistent with using your favorite products, VIP exclusive offers and discounted pricing.
No, you do not need to sign up for a subscription. However, many of our customers like to take advantage of our 10% off discount to get consistent deliveries and save money!
We stand behind each of our products and offer a 30-day Satisfaction Guarantee return policy. If you are not completely satisfied with any of our products, just return the unused portion to us within 30 days and we will refund your purchase price (minus a $9.95 restocking fee).
Yes! We accept returns on UNOPENED products within our 30 day return policy.
Yes! All NatureM.D. products are designed to work together.
It is best to take it 1-2x a day, many people take it after brushing teeth or after a meal.
The natural flavoring is a proprietary blend of natural herbs and spices.
The shelf life is 2 years.
This product can be enjoyed long-term.
Oral health and gut health are closely connected through the mouth-gut axis. The mouth is the entry point for food and bacteria, so an imbalance in the oral microbiome can impact the gut. Harmful bacteria in the mouth can travel to the digestive system, leading to inflammation, infections, and digestive issues like leaky gut. Maintaining a healthy oral microbiome can help prevent harmful bacteria from entering the gut, supporting better digestion, immune function, and overall gut health. Essentially, a healthy mouth helps create a healthier gut.
Yes, oral probiotic supplements may help with oral thrush (candidiasis) by restoring balance to the oral microbiome and potentially reducing yeast overgrowth. Probiotics can help by competing with Candida for resources, potentially reducing the fungus's ability to thrive. Some studies have shown that specific probiotic strains can even stimulate the production of antibodies to Candida antigens.