OralBiome 365
OralBiome 365
OralBiome 365
OralBiome 365
OralBiome 365
OralBiome 365
OralBiome 365

OralBiome 365

OralBiome 365

New Arrival

OralBiome™ 365 is your daily 3-in-1 formula designed to support a healthy mouth, balanced gut, and strong immune system — all in a refreshingly minty chewable tablet.

  • 90 CHEWABLES PER BOTTLE
  • ALL-NATURAL INGREDIENTS
  • 3 CLINICALLY PROVEN PROBIOTIC STRAINS
  • REFRESHING VANILLA MINT FLAVOR

30-day money back guarantee

Benefits

The Daily Mint That Does More Than Freshen Breath

  • Supports Healthy Teeth & Gums – Formulated with Vitamin D, Calcium, and Vitamin K to help strengthen teeth, nourish gums, and promote long-term oral wellness from within.
  • Balances Your Gut Microbiome – Includes three clinically studied, spore-forming probiotic strains that survive harsh stomach acid and go to work where it matters — restoring gut balance and supporting healthy digestion.
  • Strengthens Immune Defenses – Infused with Zinc and Vitamin C to help power up your immune system and keep you feeling your best, day after day.
  • Freshens Breath, Naturally
    Clean, minty flavor meets probiotic support for oral bacteria
    – helping to reduce bad breath at the source for lasting freshness.

How to use

Chew 1 tablet daily. No water needed. Perfect for mornings, after meals, or anytime.

Supplement Facts

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Non-GMO Allergen Free Vegan Certified Made in the USA
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3 Clinically Proven PROBIOTIC Strains

ALL-NATURAL INGREDIENTS

Dairy-Free

Allergen-Free

Clinically-Studied Ingredients

3 Clinically Proven PROBIOTIC Strains

ALL-NATURAL INGREDIENTS

Dairy-Free

Allergen-Free

Clinically-Studied Ingredients

Your Key to Better Oral & Gut Health

Your Key to Better
Oral & Gut Health

Total Oral Health Support
Gut Microbiome Balance
Immune System Boost
3-in-1 Formula

Surface Care Isn’t Enough

Many people think that brushing and flossing alone are enough to maintain oral health — but even with the best habits, issues like sensitive gums, weakened enamel, and lingering bad breath can persist. That’s because oral health isn’t just about surface care; it’s deeply connected to internal nutrition and the balance of good bacteria in your mouth. Without the right nutrients and support, you may find that your teeth and gums stay vulnerable over time.

OralBiome365 strengthens your teeth, gums and bone density with a powerful trio of Vitamin D, Calcium, and Vitamin K — nourishing gum tissue and laying the foundation for long-term oral wellness.

Total Oral Health Support
Gut Microbiome Balance
Immune System Boost
3-in-1 Formula

Gut Imbalance Disrupts More Than Digestion

An imbalanced gut microbiome can quietly affect your digestion, your energy levels, and even your immune system — but it often goes unnoticed until uncomfortable symptoms like bloating, irregularity, and food sensitivities start to disrupt your daily life. Stress, poor diet, travel, and antibiotics can all throw off the delicate balance of your gut flora, making it harder for your body to digest food properly and absorb nutrients efficiently.

OralBiome™365 delivers three tough, clinically-studied probiotic strains designed to survive harsh stomach acid to reach your gut alive — helping to restore and rebalance your microbiome and support smoother digestion.

Total Oral Health Support
Gut Microbiome Balance
Immune System Boost
3-in-1 Formula

Everyday Stress Can Weaken Your Defenses

When your immune system is compromised, everything feels harder — from fighting off seasonal colds to recovering quickly from minor illnesses. Chronic stress, poor gut health, and lack of essential nutrients like Vitamin C and Zinc can quietly erode your body’s defenses over time, leaving you feeling drained, vulnerable, and more susceptible to everyday health challenges.

OralBiome™365 provides a daily boost with immune-supporting nutrients like Zinc and Vitamin C, helping to strengthen your natural defenses so you can stay resilient, energetic, and better protected against oxidative stress.

Total Oral Health Support
Gut Microbiome Balance
Immune System Boost
3-in-1 Formula

Juggling Multiple Supplements is Exhausting

Most people have good intentions when it comes to their health, but taking multiple supplements every day can quickly become overwhelming, expensive, and hard to maintain. Missing a few days here and there can lead to inconsistent results, and busy schedules make it even tougher to stick to complex wellness routines.

OralBiome™365 makes daily health simple by combining oral, digestive, and immune support into one refreshing mint-flavored chewable. With no pills to swallow, no water needed, and no refrigeration required, it’s a hassle-free way to give your body consistent, effective support every day.

All the benefits in one serving

All the benefits in
one serving

OralBiome 365 supports your mouth, gut, and immune system with targeted probiotics and essential nutrients.

FAQ's

Adults Chew 1-2 capsules per day

It supports both oral and gut health by balancing the mouths microbiome, improving digestion and promoting a stronger immune system. It helps to prevent issues like gum inflammation, bad breath, and leaky gut while boosting nutrient absorption.

1-2 weeks you will notice fresher breath and improved gum health. For noticable improvements in digestive heatlh, it can take 3-4 weeks of consistent use.

It is great for anyone looking to improve overall oral hygiene, digestive health and immune function.

It is Certified Vegan, soy free, Non-GMO, dairy free, sugar free, and gluten free.

We recommend you consult with your physician. All of our products are made with natural ingredients.

It’s always best to consult a doctor before taking any supplement, including Oral Biome, during pregnancy or while nursing. Although probiotics are generally considered safe, every pregnancy is different, and a healthcare professional can provide personalized advice to ensure both the mother's and baby’s health are prioritized. Always check with a doctor before introducing new products while pregnant or breastfeeding.

Recurring deliveries keep you consistent with using your favorite products, VIP exclusive offers and discounted pricing.

No, you do not need to sign up for a subscription. However, many of our customers like to take advantage of our 10% off discount to get consistent deliveries and save money!

We stand behind each of our products and offer a 30-day Satisfaction Guarantee return policy. If you are not completely satisfied with any of our products, just return the unused portion to us within 30 days and we will refund your purchase price (minus a $9.95 restocking fee).

Yes! We accept returns on UNOPENED products within our 30 day return policy.

Yes! All NatureM.D. products are designed to work together.

It is best to take it 1-2x a day, many people take it after brushing teeth or after a meal.

The natural flavoring is a proprietary blend of natural herbs and spices.

The shelf life is 2 years.

This product can be enjoyed long-term.

Oral health and gut health are closely connected through the mouth-gut axis. The mouth is the entry point for food and bacteria, so an imbalance in the oral microbiome can impact the gut. Harmful bacteria in the mouth can travel to the digestive system, leading to inflammation, infections, and digestive issues like leaky gut. Maintaining a healthy oral microbiome can help prevent harmful bacteria from entering the gut, supporting better digestion, immune function, and overall gut health. Essentially, a healthy mouth helps create a healthier gut.

Yes, oral probiotic supplements may help with oral thrush (candidiasis) by restoring balance to the oral microbiome and potentially reducing yeast overgrowth. Probiotics can help by competing with Candida for resources, potentially reducing the fungus's ability to thrive. Some studies have shown that specific probiotic strains can even stimulate the production of antibodies to Candida antigens.